By Mary Kundert

The Corner Pharmacist

Dear Mary: Until recently, I’ve been able to remain very active in sports. I have always been quite healthy and have kept myself in shape through diet and exercise. I enjoy working out, but recently I have noticed increased pain in my knees.

I played collegiate basketball back in the 1970s and have had a few sports injuries. I’d like to know more about alternative treatments for joint injuries, such as glucosamine.

Tom, Los Altos Hills

Dear Tom: Glucosamine is a nutritional supplement used to repair and reduce joint damage. The sulfate (SO4) form is the one that has been most studied, and is typically recommended. People who are reducing their sodium (NaCl) intake should check the label and use a preparation of glucosamine sulfate with potassium chloride (KCl). These mineral salts are used to stabilize the formulation.

I like glucosamine sulfate. While anti-inflammatory drugs mask symptoms, they do nothing to treat the cause of the problem. Glucosamine, on the other hand, provides the body with the building blocks necessary for cartilage growth. For this reason, do not expect quick relief. It can take two to three months to see the full benefits.

The usual dosage is 500mg three times a day. This supplement is extremely well tolerated, with reports of side effects being both rare and mild in all age groups. Allergic reactions are also very rare, even though glucosamine is derived from the shells of shellfish. People who are allergic to shellfish are typically reacting to a substance in the meat of the animal, and all such compounds are thoroughly removed during glucosamine production.

Nevertheless, you can always start off taking one capsule or tablet a day to be safe. There are no reported interactions with food, drugs or herbs.

Several people have asked whether glucosamine is safe for diabetics. Recent studies point to the possibility that it might interfere with blood sugar regulation. Consult with your doctor and monitor your blood sugar if you are concerned.

Glucosamine is often sold combined with chondroitin sulfate, a major constituent in cartilage.

The latest studies seem to indicate that the two together are more effective than either one alone, though this view is not shared by all.

Kundert is available by appointment only for 10-minute consultations sponsored by Los Altos Pharmacy. To make an appointment, call 948-1212.